- by Medikoe Health Expert
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- Feb 12 2017
What is Anaplasia?
A condition where cells lose their morphological characteristics due to poor cell differentiation is called anaplasia. The cells lose their morphological characteristics and orientation due to anaplasia.
Changes caused by Anaplasia
- Cells turn malignant
- Loss of structural differentiation
- Loss of functional differentiation
- Large and darkly stained nuclei
- 1:1 nuclear-cytoplasmic ratio as against the normal 1:4 and 1:6
- Cells larger than normal and contain either one large nucleus or many nuclei
- Coarse and clumped chromatin
- Nuclei are variable and weirdly shaped
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