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Azithromycin: Side Effects, dosage, COVID-19 (under study)

Medikoe Health Expert

Medikoe Health Expert

  Koramangala, bengaluru, karnataka, india, Bengaluru     Jul 12, 2021

   2 min     

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Overview

Azithromycin is a prescription drug utilised in the treatment of infections caused due to some bacterias. The drug should not be used in the treatment of infections caused due to viruses like the common cold. It is available as an oral suspension, an oral tablet, an eye drop or in an IV form. Azithromycin can be used in combination alongwith additional antibiotics when it is used in the treatment of infections, including Mycobacterium avium complex and some STIs (sexually transmitted infections).

How it works

Azithromycin works by stopping bacteria from reproducing (making more bacteria). This action eliminates the bacteria and helps in the treatment of your infection.

Azithromycin for COVID-19

The health crisis triggered due to the COVID-19 pandemic has led to the heavy use of pharmacological procedures and treatments whose effectiveness has not been adequately evidenced. Increasingly, thanks to the effects of standardised clinical trials, the effectiveness of the various treatments used are becoming more apparent, of which only tocilizumab and dexamethasone have so far been revealed to lessen mortality associated with COVID-19 infection. 

Azithromycin has been one of the most extensively used medications in the treatment of COVID-19 since it has been recognised for its immunomodulatory effects and antiviral properties, from which benefits have been achieved in the treatment of other respiratory diseases as well. 

Azithromycin exhibits in vitro activity against SARS-CoV-2 and could help in different phases of the viral cycle. Its immunomodulatory properties incorporate the capability to downregulate cytokine production, prevent lung fibrosis or regulate epithelial cell integrity. Azithromycin treatment was associated with a decrease in ventilation days and mortality in other viral infections. These attributes could be beneficial throughout the COVID-19 treatment. However, the data confirming its use is of low quality and scarce. Azithromycin has been evaluated in retrospective observational studies essentially in combination with hydroxychloroquine, which again has shown to contribute no benefit. This macrolide exhibits a well-known safety profile. Forthcoming clinical trials will conclude the role of azithromycin in the COVID-19 treatment (including the point of the disease where it extends the greatest benefits and the effect of its combination with additional drugs).

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Tags:  Medicines,viral infection,virus infection,bacterial infections,Allergies and Infections,Diseases ,Azithromycin, COVID-19 treatment, COVID-19 pandemic, respiratory diseases, SARS-CoV-2, treatment of infections, prescription drug

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